Circadian Oscillation and Stochastic Noises
نویسندگان
چکیده
Various organisms (microbes, plants, and mammals) have own circadian rhythm and an endogenous timekeeping. All organisms have approximately 24 hours periodic rhythm, although the mechanisms and factors for oscillation production are different [1]. Even in the same cell, the expression level of genes should be different and amount of the proteins should stochastically differ [3]. To keep the precise rhythm, cells should have the system to overcome the stochastic noises. In order to identify this maintenance mechanism of the circadian oscillation, we tried extensive simulation of Drosophila circadian oscillation using a biological simulator, “Biobje” [4].
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